Currently there are definitions from many agencies and research societies defining "bioinformatics" as deriving knowledge from computational analysis of large volumes of biological and biomedical data. Should this be the bioinformatics research focus? We will discuss this issue in this review article. We would like to promote the idea of supporting human-infrastructure (HI) with no-boundary thinking (NT) in bioinformatics (HINT).1
  1. Huang, X. et al. No-boundary thinking in bioinformatics research. BioData mining 6, 19 (2013).
  2. Huang, X. et al. Big data - a 21st century science Maginot Line? No-boundary thinking: shifting from the big data paradigm. BioData Mining 8, 7 (2015).
  3. Moore, J. H. et al. No-boundary thinking in bioinformatics. Biocomputing 2017 646–648.